Journal of Pathology and Translational Medicine

Kyung Ha Kang

5 Articles

Polymorphic Reticulosis.: Duck Hwan Kim, Jin Hee Sohn, Sung Suk Paeng, Kyung Ha Kang, Jung Il Suh; Korean J Pathol. 1995;29(3):296-302.

Abstract PDF: Polymorphic reticulosis(PMR) is a unique clinicopathological entity of unknown etiology, which commonly present as an aggressive, necrotizing lesion of the upper respiratory tract. It is a separate nosologic entity from Wegener's granulomatosis and idiopathic mildine destructive disease. The origin of the cells composing polymorphic reticulosis has been controversial. We reviewed 15 cases of polymorphic reticulosis with respect to clinical and histologic bases, and immunohistochemical studies were done using UCHLI (CD45RO), as a T cell marker, CD-20 as a B cell marker and alpha- I -antichymotrypsin as a histiocytic marker. Almost all cases showed characteristic histologic and immunohistochemical features similar to those of peripheral T cell lymphoma. Thus, this study indidcated that polymorphic reticulosis is a type of malignant lymphoma of T cell lineage.

Meckel-Gruber Syndrome: An autopsy case report.: Kyung Ha Kang, Duck Hwan Kim, Hee Jin Chang, In Sook Kim, Jin Hee Sohn, Jung Il Suh; Korean J Pathol. 1994;28(2):200-202.

Abstract PDF: Meckel-Gruber syndrome is a quite rare congenital disorder, characterized by posterior encepalocele, cleft palate and lip, polycystic kidneys, hepatic fibrosis with bile duct proliferation, and postaxial polydactyly and syndactyly. We experienced an autopsy case of M eckel-Gruber syndrome in a second baby of 28 year-old woman. At 26 weeks of gestation, congenital anomaly was detected on ultrasonographic examination and the pregnancy was terminated. Familial history was not noted.

Cytologic Features of Soft Tissue Sarcoma in the Aspiration Biopsy Cytology.: Jin Hee Sohn, Duck Hwan Kim, Kyung Ha Kang, In Sook Kim, Jung Il Suh; Korean J Cytopathol. 1994;5(1):28-34.

Abstract PDF: Aspiration biopsy cytology is a convenient, easy and non-invasive method for diagnosis of tumors. The results and cytologic features of carcinoma in various organs have been reported frequently, however, those of soft tissue sarcoma are relatively rare to find.

A Study of Nucleolar Organizer Regions in Normal and Neoplastic Epithelial Cells of Stomach.: Hee Jin Chang, Kyung Ha Kang, Jung Hee Park, Jin Hee Sohn, Jung Il Suh; Korean J Pathol. 1992;26(5):451-458.

Abstract PDF: Nucleolar organizer regions are DNA loops encoding rihbosomal RNA production and detectable by the argyrophilia of their associated proteins(AgNORs). AgNOR numbers correlate with cellular proliferating activity. Many studies have shown a significnt difference in AgNOR counts between benign and malignant tumors. AgNOR counts were also helpful in differential diagnosis. For the evaluation of its diagnostic utility in gastric lesions, a silver staining technique was carried out in paraffin sections of 5 control cases, 5 benign peptic ulcers, 7 hyperplastic polyps, 10 tubular adenomas, 16 early gastric adenocarcinomas and 15 advanced gastric adenocarcinomas. The results were as follows. The mean numbers of AgNORs in early and advanced gastric adenocarcinomas(1.94 and 2.16) were significantly higher than those of normal foveolar epithelium(1.43) and epithelia of benign gastric ulcers(1.54), hyperplastic polyps(1.64) and tubular adenomas(1.79). In malignancy, there was increased variability in size and shape of AgNORs. There was little differences in mean AgNOR numbers between early and advanced gastric adenocarcinomas. Differentiation of the tumor made no difference in AgNOR numbers. From the above results, the AgNORs count, if its morphologic change are taken into consideration, is helpful in differentiation between malignant and non-malignant lesions.

Cytologic feature of papillary carcinoma of the thyroid.: Jeong Hee Park, Hee Jin Chang, Kyung Ha Kang, Jin Hee Sohn, Jung Il Suh; Korean J Cytopathol. 1991;2(2):111-118.

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